Friedman Fellows eLibrary

FriedmanDiabetesInstitute.com is the host for the Friedman Fellows website. The Friedman Fellows represent the following institutions:  Beth Israel Medical Center/Albert Einstein College of Medicine, Tufts Medical Center/Endocrinology Division, Friedman School of Nutrition/Tufts University, UCLA Medical Center/David Geffen School of Medicine, Mount Sinai Medical Center/Mount Sinai School of Medicine, Brigham and Women’s Hospital/Harvard Medical Center, Siouxland Medical Education Foundation. Fellows' publications can be viewed below and Fellows' names are linked to their respective profile pages.
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2009

Activation of the calcium receptor stimulates gastrin and gastric acid secretion in healthy participants
Ceglia L, Harris SS, Rasmussen HM and Dawson-Hughes B
Osteoporosis Int 2009 (20): 71-78 © International Osteoporosis Foundation and National Osteoporosis Foundation 2008
KEYWORDS: Calcimimetic, Calcium sensing receptor, Gastric acid, Gastrin
Association between serum osteocalcin and markers of metabolic phenotype
Pittas AG, Harris SS, Eliades M, Stark P and Dawson-Hughes B
J Clin Endocrinol Metab 2009:94(3):827-832 © 2009 by The Endocrine Society
Genetic and environmental influences on factors associated with cardiovascular disease and the metabolic syndrome
Das SK, Saltzman E, Gilhooly CH, Delany JP, Golden JK, Pittas AG, Dallal GE, Bhapkar MV, Fuss PJ, Dutta C, McCrory MA, Roberts SB
Obesity 2009 Apr 23
Genetic and environmental influences on factors associated with cardiovascular disease and the metabolic syndrome
Elder SJ, Lichtenstein AH, Pittas AG, Roberts SB, Fuss PJ, Greenberg AS, McCrory MA, Bouchard TJ, Edward Saltzman E, and Neale MC
J Lipid Res 2009 Apr 16
KEYWORDS: twins, heritability, genetics, risk factors
Impact of supplementation with bicarbonate on lower-extremity muscle performance in older men and women
B. Dawson-Hughes, C. Castaneda-Sceppa, S. S. Harris, N. J. Palermo, G. Cloutier, L. Ceglia, G. E. Dallal
2009 August 13. © International Osteoporosis Foundation and National Osteoporosis Foundation 2009
KEYWORDS: Muscle endurance, Muscle power, Nitrogen excretion, Potassium bicarbonate
Inhaled insulin. What went wrong
Mitri J and Pittas AG
Nature Reviews Endocrinology 2009:5(1):24-5
Insulin sensitivity in African-American and white women: Association with inflammation
Hyatt TC, Phadke RP, Hunter GR, Bush NC, Munoz AJ, Gower BA
Obesity 17: 276-282, 2009
Obesity attenuates the contribution of African admixture to the insulin secretory profile in peripubertal children: A longitudinal analysis
Casazza K, Phadke RP, Fernandez JR, Watanabe RM, Goran MI, Gower BA
Obesity, in press
Plasma 25-hydroxyvitamin D is associated with markers of the insulin resistance phenotype in nondiabetic adults
Liu E, Meigs JB, Pittas AG, McKeown NM, Economos CD, Booth SL, Jacques PF
J. Nutr 2009:139(2):329-34 © 2009 American Society for Nutrition
Potassium Bicarbonate Attenuates the Urinary Nitrogen Excretion That Accompanies an Increase in Dietary Protein and May Promote Calcium Absorption
Lisa Ceglia, Susan S. Harris, Steven A. Abrams, Helen M. Rasmussen, Gerard E. Dallal, and Bess Dawson-Hughes
J Clin Endocrinol Metab, February 2009, 94(2):645–653. © 2009 by The Endocrine Society
A Simple Single Serum Method to Measure Fractional Calcium Absorption using Dual Stable Isotopes
L. Ceglia, S. A. Abrams, S. S. Harris, H. M. Rasmussen, G. E. Dallal, B. Dawson-Hughes
DOI 10.1055/s-0029-1234088, Published online: 2009, Exp Clin Endocrinol Diabetes, © J. A. Barth Verlag
KEYWORDS: fractional calcium, absorption, stable isotopes, 44 Ca, 42 Ca
Using the Thrifty Food Plan to Assess the Cost of a Nutritious Diet
Parke E. Wilde, Joseph Llobrera
The Journal of Consumer Affairs, Vol. 43, No. 2, 2009, ISSN 0022-0078, Copyright 2009 by The American Council on Consumer Interests
Vitamin D and its role in skeletal muscle
Lisa Ceglia
Curr Opin Clin Nutr Metab Care 12:628–633. © 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins 1363-1950
KEYWORDS: physical performance, skeletal muscle, Vitamin D, Vitamin D receptor
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2008

Activation of the calcium sensing receptor stimulates gastrin and gastric acid secretion in healthy participants
L. Ceglia, S. S. Harris, H. M. Rasmussen, B. Dawson-Hughes
2008 June 7. © International Osteoporosis Foundation and National Osteoporosis Foundation 2008
KEYWORDS: Calcimimetic, Calcium sensing receptor, Gastric acid, Gastrin
Alkaline diets favor lean tissue mass in older adults
Bess Dawson-Hughes, Susan S Harris, and L. Ceglia
Am J Clin Nutr 2008;87:662–5. Printed in USA. © 2008 American Society for Nutrition
KEYWORDS: Urinary potassium, percentage lean body mass, humans
The association between glycemia and endothelial function in non-diabetic individuals: the importance of body weight
Voidonikola PT, Stamatelopoulos KS, Alevizaki M, Kollias G, Zakopoulos N, Lekakis J, Anastasiou E, MDa, Theodorakis M, Pittas AG and Papamichael CM
Obesity 2008: Dec 16(12):2658-62
Cardiovascular risk factors in adult patients with multisystem Langerhans-cell histiocytosis: evidence of glucose metabolism abnormalities
Alexandraki KI, Makras P, Protogerou AD, Dimitriou K, Stathopoulou A, Papadogias DS, Voidonikol P, Piaditis G, Pittas AG, Papamichael CM, Grossman AB and Kaltsas G
Q J Med 2008 Jan 101(1):31-40 © The Author 2008
Diabetes mellitus and risk of non-Hodgkin’s lymphoma: A meta-analysis of observational studies
Mitri J, Castillo J, and Pittas AG
Diabetes Care 2008:31(12) 2391-7 © 2008 by the American Diabetes Association
Inpatient Medical Errors Involving Glucose Lowering Medications and Their Impact on Patients. A review of 2598 incidents from a voluntary Electronic Error Reporting Database
RE Amori, AG Pittas, RD Siegel, S Kumar, J Chen, S Karnam, SH Golden, D Salem
Endocr Pract. 2008; 14: 535-542 © 2008 AACE
Long-term effects of energy-restricted diets differing in glycemic load on metabolic adaptation and body composition
Das SK, Gilhooly CH, Golden JK, Pittas AG, Fuss PJ, Dallal GE, McCrory MA, Saltzman E and Roberts SB
The Open Nutr J 2008 (2) 76-85
KEYWORDS: Glycemic load, caloric restriction, body weight, metabolic rate
Vitamin D and skeletal muscle tissue and function
Lisa Ceglia
0098-2997/$. © 2008 Elsevier Ltd. doi:10.1016/j.mam.2008.07.002
KEYWORDS: Vitamin D, Skeletal muscle, Vitamin D receptor, Osteomalacic myopathy
Why WAIT Program: A Novel Model for Diabetes Weight Management in Routine Clinical Practice
Hamdy O, AGoebel-Fabbr Ai, Carver C, Arathuzik G, Shahar J, Capelson R, Beaton J, O’Donnell S, El Sayed N, Mitri J, Mentzelopoulos V, Abrahamson MJ
Obesity Management, 4(4): 176-183, 2008 © Mary Ann Liebert, Inc
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2007

Adverse Effects of Incretin Therapy for Type 2 Diabetes. Author Reply
Pittas AG, Amori R and Lau J
JAMA 2007:298(15):1760 © 2007 American Medical Association
Effect of Chromium Supplementation on Glucose Metabolism and Lipids: A Systematic Review of Randomized Controlled Trials
Balk ME, Tatsioni A, Lichtenstein AH, Lau J and Pittas AG
Diabetes Care 2007:30(8):2154-2163 © 2007 by the American Diabetes Association
Effect of Chromium Supplementation on Glucose Metabolism and Lipids: A Systematic Review of Randomized Controlled Trials. Response to Kleefstra, Houweling, and Bilo
Balk EM, Lichtenstein AH, Anastassios G. Pittas AG
Diabetes Care 2007:30:e103 DOI: 10.2337/dc07-1121
Effect of inhaled insulin on fasting and postprandial plasma glucose
Ceglia L, Lau J and Pittas AG
Ann Intern Med 2007:146(11):821-822
The Effects of Calcium and Vitamin D Supplementation on Blood Glucose and Markers of Inflammation in Non-diabetic Adults
Pittas AG, Harris S, Stark P and Dawson-Hughes B
Diabetes Care 2007:30(4):980-986 © 2007 by the American Diabetes Association
The Effects of Calcium and Vitamin D Supplementation on Blood Glucose and Markers of Inflammation in Non-diabetic Adults (Comments & Responses)
Pittas AG and Dawson-Hughes B
Diabetes Care 2007:30(7):e81; Author reply e82
Efficacy and Safety of Incretin Therapy in type 2 Diabetes. Systematic review and meta-analysis of randomized control trials
RE Amori, J Lau, AG Pittas
JAMA July 2007; 298(2):194-206 © 2007 American Medical Association
Interactions among Peroxisome Proliferator Activated Receptor-y, Insulin Signaling Pathways, and Steroidogenic Acute Regulatory Protein in Human Ovarian Cells
Donna Seto-Young, Dimiter Avtanski, Marina Strizhevsky, Grishma Parikh, Parini Patel, Julia Kaplun,
Kevin Holcomb, Zev Rosenwaks, and Leonid Poretsky
The Journal of Clinical Endocrinology & Metabolism 92(6):2232–2239, © 2007 by The Endocrine Society
Long-term effects of 2 energy-resticted diets differing in glycemic load on dietary adherences, body composition, and metabolism in CALERIE, a 1-year randomized controlled trial
Das SK, Gilhooly CH, Golden JK, Pittas AG, Fuss JP, Cheatham RA, Tyler S, Tsay M, McCroy MA, Lichtenstein AH, Dallal GE, Dutta C, Bhapkar MV, DeLany JP, Saltzman E and Roberts SB
Am J Clin Nutr 2007:85:1023 © 2007 American Society for Nutrition
KEYWORDS: Glycemic load, caloric restriction, body weight, metabolism
Management of Glycemia in Patients With Diabetes Mellitus and CKD
Noah D. Lubowsky, MD, Richard Siegel, MD, and Anastassios G. Pittas, MD, MS
American Journal of Kidney Diseases, Vol 50, No 5 (November), 2007: pp 865-879
KEYWORDS: Diabetes mellitus; chronic kidney disease
Pharmacotherapy for Obesity
Neff LM and Aronne LJ
Curr Atheroscler Rep 2007; 9:454-462. © by Current Medicine Group LLC
The Role of Vitamin D and Calcium in type 2 diabetes. A Systematic Review and Meta-Analysis
Pittas AG, Lau J, Hu F and Dawson-Hughes B.
J Clin Endocrinol Metab 2007:92:2017-2029 © 2007 by The Endocrine Society
Temozolomide in the treatment of an invasive prolactinoma resistant to dopamine agonists
Neff LM, Weil M, Cole A, Hedges TR, Shucart W, Lawrence D, Zhu J, and Lechan RM
Pituitary 2007;10:81-86 © Springer Science+Business Media, LLC 2007
KEYWORDS: Prolactinoma, Temozolomide, Dopamine agonist resistance
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2006

Dietary composition and weight loss: can we individualize dietary prescriptions according to insulin sensitivity or secretion status?
Pittas AG and Roberts SB
Nutr Rev October 2006:64(10): 435-448. © 2006 International Life Sciences Institute
KEYWORDS: dietary composition, insulin secretion, insulin sensitivity, weight loss
The effects of the dietary glycemic load on type 2 diabetes risk factors during weight loss
Pittas AG, Roberts SB, Das SK, Gilhooly CH, Golden J, Saltzman E, Stark PC and Greenberg AS
Obesity 2006: 14(12): 2200-2209. © 2006 NAASO
KEYWORDS: glycemic index, glucose tolerance, insulin sensitivity, insulin secretion, C-reactive protein
Meta-Analysis: Efficacy and Safety of Inhaled Insulin Therapy in Adults with Diabetes Mellitus
Lisa Ceglia, MD, Joseph Lau, MD, and Anastassios G. Pittas, MD, MS
2006 November 7. Annals of Internal Medicine, Volume 145, Number 9
Hyperglycemia and Insulin Therapy in Critical Illness
Patel A and Pittas AG
CAMJ 2006:174(7): 917-8 © 2006 CMA Media Inc
Insulin therapy and in-hospital mortality in critically ill patients: Systematic review and meta-analysis of randomized controlled trials
Pittas AG, Siegel RD and Lau J
J Parenter Enteral Nutr 2006:30(2): 164-172 © 2006 by the American Society for Parenteral and Enteral Nutrition
Vitamin D and Calcium Intake in Relation to type 2 Diabetes
Pittas AG, Dawson-Hughes B, Li T, Willett WC, Van Dam RV, Manson JE and Hu FB
Diabetes Care 2006:29(3): 650-6 © 2006 by the American Diabetes Association
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2005

The impact of admission hyperglycemia on hospital mortality in various intensive care unit populations
Whitcomb, BW, Pradhan EK, Pittas AG, Roghmann MC and Perencevich EN
Crit Care Med 2005:33: 2772-2777 © Lippincott, Williams & Wilkins
KEYWORDS: hyperglycemia; diabetes mellitus; intensive care unit; mortality; effect modification
Interstitial Glucose Level is a Significant Predictor of Energy Intake in Free-Living Women with Healthy Body Weight
Pittas AG, Hariharan R, Stark PC, Hajduk CL, Greenberg AS, Roberts SB
J Nutr 2005 May; 135(5):1070-4 © 2005 American Society for Nutritional Sciences
KEYWORDS: glucose, energy, hunger, satiety, free-living
Leukopenia and thrombocytopenia caused by thiazolidinediones
Digman C, Klein A and Pittas AG
Ann Intern Med 2005:143(6): 465 © 2005 American College of Physicians
the literature: new and noteworthy nutrition research
Neff LM
In Nutr Clin Care 2005;8:2-5
A low glycemic load diet facilitates greater weight loss in overweight adults with high insulin secretion but not in overweight adults with low insulin secretion in the CALERIE trial.
Pittas AG, Das SK, Hajduk CL, Golden J, Saltzman E, Stark PC, Greenberg AS and Roberts SB
Diabetes Care 2005:28(12): 2939-41 © 2005 by the American Diabetes Association
The role of the primary care physician before and after weight loss surgery
Neff LM and Saltzman E
Obesity Management. 2005;1:147-54
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2004

FDA / AHRQ Evidence-Based Report
Balk E, Tatsioni A, Chung M, Pittas AG, Lichtenstein A and Lau J
Health claims of Chromium Picolinate on Insulin Resistance and Cardiovascular Disease. September 21, 2004
HOT TOPIC: Adipocytokines and insulin resistance
Pittas AG, Joseph N and Greenberg AS
J Clin Endocrinol Metab 2004:89(2): 447-452 © 2004 by The Endocrine Society
Insulin therapy for critically ill hospitalized patients. A metaanalysis of randomized controlled trials
Pittas AG, Siegel RD and Lau J
Arch Intern Med 2004:164: 2005-11 © 2004 American Medical Association
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2003

Current directions in hemochromatosis research: towards an understanding of the role of iron overload and the HFE gene mutations in the development of clinical disease (brief critical review)
Neff LM
Nutr Rev 2003;61:38-42. © 2003 International Life Sciences Institute
KEYWORDS: HFE, iron overload, hemochromatosis, gene mutations
Might the diabetic environment in utero lead to type 2 diabetes?
Ordovas J, Pittas AG and Greenberg AS
Lancet 2003:361(9372): 1839-40
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2000

Bone Metastases from thyroid carcinoma: clinical characteristics and prognostic variables in one hundred forty-six patients
Pittas AG, Adler M, Fazzari M, Tickoo S, Rosai SM, Larson SM and Robbins RJ
Thyroid 2000:10 (3): 261-268
Bone metastases from thyroid carcinoma : a histopathologic study with clinical correlates
Tickoo SK, Pittas AG, Adler M, Fazzari M, Larson SM and Robbins RJ
Arch Pathol Lab Med 2000: 124 (10): 1440-7
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Prior to 2000

Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway
Hanif R, Pittas AG, Feng Y, Koutsos MI, Qiao L, Staino-Coico L, Shiff SI and Rigas B
Biochem Pharmacol 1996; 52 (2): 237-45 © 1996 Elsevier Science Inc
KEYWORDS: prostaglandins, NSAIDs, colon cancer, cell proliferation, apoptosis, cell cycle
Evidence for a membrane defect in Alzheimer’s disease brain
Nitsch RM, Blusztajn JK, Pittas AG, Slack BE, Growdon JH, and Wurtman RJ.
Proc Natl Acad Sci USA 1992: 89 (5): 1671-5